- Visibility 397 Views
- Downloads 452 Downloads
- Permissions
- DOI 10.18231/j.ijca.2025.086
-
CrossMark
Rare disorders of the immune system: Kimura’s disease and Evans syndrome – anaesthetic implications
- Author Details:
-
Pradnya Milind Bhalerao
-
Shital Mahendra Kuttarmare *
-
Amartya Chaudhuri
Pradnya Milind Bhalerao
Shital Mahendra Kuttarmare *
Amartya Chaudhuri
Background: Kimura’s disease is a rare, chronic eosinophilic inflammatory disorder that typically affects the salivary glands, skin, lymph nodes and kidneys. Evans syndrome is an autoimmune condition characterised by the simultaneous or sequential occurrence of idiopathic thrombocytopenic purpura and autoimmune haemolytic anaemia.
Case Presentations: We present two distinct cases highlighting the anaesthetic considerations in patients with rare immune disorders. The first case involves a 35-year-old male with Kimura’s disease, presenting with a post-auricular mass scheduled for surgical excision. The second case features an 18-year-old female diagnosed with Evans syndrome, who was scheduled for pan-retinal photocoagulation under topical anaesthesia due to visual disturbances.
Conclusions: Anaesthetic management of Kimura’s disease (KD) requires vigilance due to potential complications such as increased intraoperative bleeding, difficult airway management from mass effect and renal impairment associated with nephrotic syndrome. In patients with Evans syndrome, key concerns include thrombocytopenia, risk of airway bleeding, systemic involvement, and the need for perioperative corticosteroid supplementation.
Keywords: Kimura’s disease, Evans syndrome, Anaesthesia, Immune disorders, Airway management, Perioperative care.
References
- Marshall JS, Warrington R, Watson W, Kim HL. An introduction to immunology and immunopathology. Allergy Asthma Clin Immunol. 2018;14(Suppl 2):49.
- Gupta A, Shareef M, Lade H, Ponnusamy SR, Mahajan A. Kimura's Disease: A diagnostic and therapeutic challenge. Indian J Otolaryngol Head Neck Surg. 2019;71(Suppl 1):855–9.
- Baidya DK, Chhabra A, Raj R. Anaesthetic management of a patient with Kimura’s disease for superficial parotidectomy. J Anaesthesiol Clin Pharmacol. 2011;27(3):383–5.
- Mulla F, Bomanwar N, Sakhare S, Pinto CJ. Kimura's disease of the left arm. BMJ Case Rep. 2022;15(8):e250758.
- Nagaraj S, Singh SN, Sharma VK, Soni A, Harshvardhan R, Agrawal S. Kimura Disease: A case report and review of literature. Indian J Otolaryngol Head Neck Surg. 2022;74:1850–3.
- Swarnkar M, Agrawal A. Kimura’s disease. Formos J Surg. 2018;51:26–8.
- Dhingra H, Nagpal R, Baliyan A, Alva Sr. Kimura disease: case report and brief review of literature. Med Pharm Rep. 2019;92(2):195–9.
- Sorbello M, Laudini A, Morello G, Sidoti MT, Maugeri JG, Giaquinta A, et al. Anaesthesiological implications of Kimura's disease: a case report. J Med Case Rep. 2009;3:7316.
- Wakim JH, Sledge KC. Anaesthetic implications for patients receiving exogenous corticosteroids. AANA J. 2006;74(2):133–9.
- Igarashi K, Sakurai K, Takahata O, Saito T, Sakamaki Y, Sengoku K, et al. [Anesthetic management of a patient with Evans syndrome- -benefit of perioperative hemodilutional autologous blood transfusion]. Masui. 2002;51(11):1260–2.