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Haemodynamic changes and oxygen saturation during general anaesthesia in smokers and non-smokers

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Original Article

Author Details : Meenakshi Agarwal, Suresh Singh*, Satish Kumar, Shahbaz Ahmad, Santosh Kr. Sharma

Volume : 6, Issue : 3, Year : 2019

Article Page : 395-400

https://doi.org/10.18231/j.ijca.2019.076

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Abstract

Introduction and Objectives: Smoking and tobacco chewing causes many physiological changes in the body cardiovascular, cancer and pulmonary morbidity and mortality. The aim of this study is to evaluate the effect of smoking and tobacco chewing on cardio-respiratory system during preoperative and postoperative period.
Materials and Methods: The present study was conducted on patients of either sex ranging from 18-60 years of ASA (American Society of Anesthesiology) grade I and grade II scheduled for elective surgical procedures at Nehru Hospital, B.R.D. Medical College, Gorakhpur after the permission of ethical committee. Detailed history and physical examination was done. Arterial blood gas analysis was done and partial pressure of oxygen was recorded preoperatively and on postoperative day 1, 2 and 3. Patients were divided into three groups according to smoking and tobacco chewing habits. Statistical analysis was done using SPSS version 16.0 software. t-test, and Mann–Whitney test were applied according to the requirement. The level of significance was fixed at 95%. P < 0> Results: The proposed study was done on 50 patients of ASA grade I and II who were scheduled to undergo elective surgical intervention. Out of 50 patients 37 were male and 13 were female in the ratio of 2.84:1. Mean pulse rate was increased in all groups just after intubation and just after extubation but the amplitude of rise was maximum in Group-III. A significant rise in systolic blood pressure was observed in Group-I (control) just after intubation which came to basal value within 5 minutes of intubation. A significant rise in mean arterial blood pressure was observed in Group-I (control) just after intubation which came to basal value within 5 minutes of intubation.
Conclusion: Most of the smokers and tobacco chewers had significant reduction in preoperative bedside pulmonary function tests and associated decrease in partial pressure of oxygen. These patients required oxygen inhalation postoperatively to prevent hypoxia.

Keywords: Smoking and tobacco, Arterial blood pressure, Pulse rate, Oxygen.

How to cite : Agarwal M, Singh S, Kumar S, Ahmad S, Sharma S K, Haemodynamic changes and oxygen saturation during general anaesthesia in smokers and non-smokers. Indian J Clin Anaesth 2019;6(3):395-400

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