---

A comparative study of intrathecal 0.5% isobaric levobupivacaine with fentanyl and 0.5% isobaric levobupivacaine with nalbuphine in infraumbilical surgeries: A randomized double blind clinical trial

Full Text PDF

---

Original Article

Author Details : Ramesh Koppal, Dinesh Naik*, Veeresh Mathpati, Shivanand Hulkund

Volume : 6, Issue : 2, Year : 2019

Article Page : 203-208

https://doi.org/10.18231/j.ijca.2019.038

Suggest article by email

Get Permission

Abstract

Introduction: Spinal anaesthesia is most commonly used technique for lower abdominal surgeries. Its main disadvantage remains the short duration of action, hence different additives have been used. Opioids have been used to enhance the clinical efficacy and duration of action of local anesthetic drugs. The present study was aimed to compare the clinical efficiency of fentanyl and nalbuphine as an adjuvant to 0.5% Isobaric levobupivacaine for lower abdominal surgeries.
Materials and Methods: After obtaining ethical committee clearance and written consent from patient. ASA grade ?&?? patients aged between 20-60 years undergoing infra umbilical surgeries were selected divided into two groups of 45 each by computerized randomization. Group A received intrathecal fentanyl 25µg(0.5ml) with 3ml(15mg)0f 0.5% Isobaric Levobupivacaine, and group B received intrathecal nalbuphine 0.8mg(0.5ml) with 0.5% Isorbaric levobupivacaine 3ml(15mg). Statistical analysis performed by STATA 11.2. Students t test prior to find the significance difference between the study parameters.
Results: The duration of first rescue analgesia required prolonged in group B (430.3+11.13min) compared to group A is 285.97+8.8min with p value of 0.001(<0> Conclusion: Both the groups were equally efficacious with good intraoperative conditions with haemodynamic stability however group B improves the quality of intraoperative and postoperative analgesia with minimal side effects.

Keywords: Spinal anaesthesia, Nalbuphine, Levobupivacaine, Fentanyl, Postoperative analgesia.

How to cite : Koppal R, Naik D, Mathpati V, Hulkund S, A comparative study of intrathecal 0.5% isobaric levobupivacaine with fentanyl and 0.5% isobaric levobupivacaine with nalbuphine in infraumbilical surgeries: A randomized double blind clinical trial. Indian J Clin Anaesth 2019;6(2):203-208

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.