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Subacute sclerosing panencephalitis - A fatal complication of measles

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Case Report

Author Details : Mohandeep Kaur, Michell Gulabani, Vinod Bala Dhir, Rao Pal Singh

Volume : 5, Issue : 1, Year : 2018

Article Page : 159-161

https://doi.org/10.18231/2394-4994.2018.0028

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Abstract

Subacute Sclerosing panencephalitis (SSPE), also known as Dawson’s disease or measles encephalitis, is an extremely rare and fatal subacute infection caused by a persistent defective measles virus (MV). It mostly develops 7-10 years after initial MV infection and is fatal within 3 years from onset of symptoms.¹
Measles virus infection before 2 years of age has 16 times higher risk of developing SSPE as compared to infection occurring after five years of age.²
SSPE is a progressive, degenerative disease of the central nervous system that occurs several years after measles infection.
Saha et al reported an annual incidence of 21 per million population in India³ as compared to 2.4 per million population in the middle east.^4-5 
By this case report, we aim to stress on the certitude that the only definitive prevention against SSPE is timely measles vaccination.

Keywords: SSPE, Measles, Vaccination.

How to cite : Kaur M, Gulabani M, Dhir V B, Singh R P, Subacute sclerosing panencephalitis - A fatal complication of measles. Indian J Clin Anaesth 2018;5(1):159-161

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