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To Evaluate Fentanyl as an Adjuvant to Intrathecal Bupivacaine for Lower Segment Cesarean Section

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Original Article

Author Details : K. Hemnath Babu, Shashikanth G. Somani, Sonali Somani, Venugopalan VM

Volume : 3, Issue : 3, Year : 2016

Article Page : 451-454

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Abstract

Objective: To compare efficacy of subarachnoid block with bupivacaine alone and low dose bupivacaine with fentanyl as adjuvant in terms of, onset and duration of anaesthesia and post-operative analgesia.
Materials and Methods: Present prospective randomized case control study was conducted in 60 patients undergoing elective caesarean section. They were randomly divided into two groups of 30 each. Subarchnoid block was standardized. Haemodynamic parameters, onset and duration of sensory and motor blockade, post-operative analgesia and side effects (if any) were compared. Data was analysed using student’s unpaired t-test.
Results: Onset of analgesia was earlier in Group BF (1.36±1.30min) compared to Group B (1.81±1.61min) which was statistically significant(p<0.05). Duration of two segment regression in Group BF (81.21±9.40min) was significantly prolonged then Group B (62.4±14.81min) which was statistically significant(p<0.05). Duration of sensory blockade in Group BF (124±9.36min) was significantly more than Group B (104.7±6.40min) which was statistically significant(p<0.05). In Group BF, onset of motor blockade was delayed and duration of motor blockade was less as compared to Group B, which was  statistically not significant (p>0.05). Postoperative analgesia in Group BF (194±16.82min) was significantly prolonged then Group B (108.57±7.90 min) which was statistically significant(p<0.05).
Conclusion: Addition of fentanyl to bupivacaine resulted in faster onset of action and effective spinal anaesthesia with a lower dose of bupivacaine.

Keywords: Bupivacaine, Caesarean section, Fentanyl, Subarachnoid block

How to cite : Babu K H, Somani S G, Somani S, Venugopalan Vm, To Evaluate Fentanyl as an Adjuvant to Intrathecal Bupivacaine for Lower Segment Cesarean Section. Indian J Clin Anaesth 2016;3(3):451-454

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