---

Conscious sedation for cataract surgery done under retrobulbar block – a comparative study evaluating the effects of midazolam and dexmedetomidine

Full Text PDF Share on Facebook Share on Twitter

---

Null

Author Details : Iniya R, Vijay Narayanan S, Venkatesan K, Rajalekshmi M

Volume : 3, Issue : , Year : 2016

Article Page : 474-483

Suggest article by email

Get Permission

Abstract

Background: A comfortable co-operative stationary patient is essential for cataract surgery especially under retrobulbar block. This can be achieved by placing the patient under ‘conscious sedation’ in which the patient will be arousable but at the same time can tolerate pain.
Aim: To compare the efficacy of midazolam with dexmedetomidine for conscious sedation in cataract surgery with regard to anxiolysis, patient’s cooperation, haemodynamic stability, surgeon’s satisfaction, recovery profile and incidence of complications.
Materials and Methods: 90 adult patients undergoing cataract surgery were randomized to three groups. Group M (n=30) patients received midazolam in loading dose of 0.03mg/kg over 10 minutes and a maintenance dose of 0.05mg/kg/hr. Group D (n=30) patients received dexmedetomidine in loading dose of 0.3mcg/kg over 10 minutes and a maintenance dose of 0.3µg/kg/hr. Group C (n=30) are control group receiving normal saline infusion as loading and maintenance doses. Statistical analysis was done using Chi-square test and ANOVA test with p value <0.05 taken as statistically significant.
Results: Anxiolysis, patient comfort and surgeon’s satisfaction were better in midazolam and dexmedetomidine groups when compared to the control group. In dexmedetomidine group there were significant incidences of hypotension and bradycardia when compared to midazolam group. Time to achieve sedation was faster in the dexmedetomidine group than in the midazolam group.
Conclusion: Midazolam and dexmedetomidine are effective in the aspects of patient co-operation, surgeon’s comfort, sedation and recovery profiles, and is safe to administer in cataract surgeries.

Keywords: Conscious sedation, Retrobulbar block, Dexmedetomidine, Midazolam, Cataract surgery

How to cite : Iniya R, Vijay Narayanan S, Venkatesan K, Rajalekshmi M, Conscious sedation for cataract surgery done under retrobulbar block – a comparative study evaluating the effects of midazolam and dexmedetomidine. Indian J Clin Anaesth 2016;3():474-483

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.