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A comparison of oral tramadol and oral tapentadol for prevention of perioperative shivering during subarachnoid block in patients undergoing transurethral resection of prostate: A randomized control trial

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Original Article

Author Details : Vinayaka Jannu*, Namratha M , Meghana Prasad Hanagandi

Volume : 12, Issue : 1, Year : 2025

Article Page : 105-111

https://doi.org/10.18231/j.ijca.2025.016

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Abstract

Background: Postanaesthetic shivering is a frequent complication after subarachnoid block, particularly in elderly patients, and can lead to discomfort and adverse effects. Prophylactic interventions are needed to mitigate this issue and enhance patient comfort during surgery.
Aim & Objective: This randomized controlled trial (RCT) aimed to compare the efficacy of oral tramadol and tapentadol as premedications for the prevention of perioperative shivering following subarachnoid block in geriatric patients undergoing transurethral resection of the prostate (TURP).
Materials and Methods: A total of 150 elderly patients scheduled for TURP under subarachnoid block were enrolled in the study. Patients were randomized into two groups: Group A (n=75) received 50 mg of oral tramadol, and Group B (n=75) received 50 mg of oral tapentadol 90 minutes before surgery. After achieving an adequate block, body temperature (forehead and tympanic membrane), shivering grades, sedation scores, and the incidence of nausea and vomiting were recorded at regular intervals throughout the perioperative period. Data were analyzed using ANOVA, Student's t-test, test of proportions, and Fisher’s exact test where appropriate. A p-value of <0> Results: There were no significant differences between the two groups in the incidence of shivering. Mean body temperature measurements (forehead and tympanic membrane) were comparable across both groups throughout the observation period. The sedation scores between Group A and Group B showed no statistically significant differences. Four patients in Group A experienced nausea, while no such incidents were reported in Group B.
Conclusion: Both oral tramadol and oral tapentadol are equally effective as premedications for the prevention of perioperative shivering following subarachnoid block in elderly patients. However, tapentadol may be associated with a lower incidence of nausea compared to tramadol.
 

Keywords: Shivering, Tramadol, Tapentadol, Subarachnoid block.

How to cite : Jannu V, Namratha M, Hanagandi M P, A comparison of oral tramadol and oral tapentadol for prevention of perioperative shivering during subarachnoid block in patients undergoing transurethral resection of prostate: A randomized control trial. Indian J Clin Anaesth 2025;12(1):105-111

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