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Intraperitoneal local anesthetic instillation as a method to attenuate pneumoperitoneum induced hemodynamic response during laparoscopic surgeries: A randomized placebo controlled study

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Original Article

Author Details : Bharat Chandra Reddy, Murali Krishna Dommeti*, Rabbani Tappa, Gopinath Ramchandran, Venu Polapally

Volume : 11, Issue : 1, Year : 2024

Article Page : 72-77

https://doi.org/10.18231/j.ijca.2024.013

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Abstract

Background: Laparoscopy is associated with significant hemodynamic changes due to pneumoperitoneum creation. We sought to study the effectiveness of intraperitoneal local anesthetic instillation in attenuating pneumoperitoneum-mediated hemodynamic response in patients undergoing laparoscopic cholecystectomy.
Materials and Methods: This randomized study was conducted after approval from the institutional ethics committee, and 100 patients were randomly assigned to either group R (40 mL of 0.2% Ropivacaine intraperitoneally) or group N (40 mL of 0.9% normal saline intraperitoneally). Data analysis was performed using SPSS version 23. Independent Samples T test was used to compare hemodynamic variables between groups at regular intervals. Statistical significance was set less than 0.05.
Results: Heart rate, systolic blood pressure, diastolic blood pressure, and mean arterial blood pressure were significantly lower in Group R than in Group N at 15,30, 45,60,75, and 90 min (P<0> Conclusion: Intra peritoneal instillation of 0.2% Ropivacaine in laparoscopic cholecystectomy attenuates intra operative hemodynamic changes associated with pneumoperitoneum.
 

Keywords: Laparoscopy, Intra peritoneal, Hemodynamic, Ropivacaine, Pneumoperitoneum.

How to cite : Reddy B C, Dommeti M K, Tappa R, Ramchandran G, Polapally V, Intraperitoneal local anesthetic instillation as a method to attenuate pneumoperitoneum induced hemodynamic response during laparoscopic surgeries: A randomized placebo controlled study. Indian J Clin Anaesth 2024;11(1):72-77

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