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The efficacy of propofol and etomidate for sedation in endoscopic bronchial ultrasound- A randomized controlled study

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Original Article

Author Details : Ganesh Ghongate, Naveen Gavel, Rajendra Gosavi, Deepak Phalgune*

Volume : 9, Issue : 2, Year : 2022

Article Page : 263-268

https://doi.org/10.18231/j.ijca.2022.050

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Abstract

Introduction: There is paucity of Indian data regarding the use of sedation for endobronchial ultrasound. We compared the efficacy of etomidate and propofol in patients undergoing endoscopic bronchial ultrasound for the achievement of satisfactory sedation.
Materials and Methods: Seventy patients aged more than 18 years posted for endoscopic bronchial ultrasound under sedation for diagnostic and therapeutic purpose were included in this randomised double- blind controlled study. Patients were randomly allocated to propofol and etomidate group. Comparison of cardiovascular adverse events and haemodynamic parameters were the primary objectives. Comparison of gag reflex, visual analogue scale score and recovery from sedation using Modified Aldrete Score were the secondary objectives.
Results: Patient satisfaction in terms of visual analogue scale score was the same in both propofol and etomidate groups. Endoscopist’s satisfaction was significantly higher in etomidate group as compared to propofol group. The post-operative hypotension was significantly lower in etomidate group as compared to propofol group. The post-operative bradycardia was significantly lower in etomidate group as compared to propofol group.
Conclusions: Endoscopist’s satisfaction and the haemodynamic control was better in etomidate group as compared to propofol group during endobronchial ultrasound.
 

Keywords: Endobronchial ultrasound, Etomidate, propofol, Gag reflex, Visual analogue scale, Haemodynamic parameters

How to cite : Ghongate G, Gavel N, Gosavi R, Phalgune D, The efficacy of propofol and etomidate for sedation in endoscopic bronchial ultrasound- A randomized controlled study. Indian J Clin Anaesth 2022;9(2):263-268

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