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Does Dexamethasone Improves Postoperative Day Care Surgery Outcome When Used As Additive To Local Infiltration Anesthesia: A Randomized case control study

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Original Article

Author Details : Rajesh Subhedar, Shakuntala Shelke, Rupali Patil, Ajay Subhedar, Vishal Ambre

Volume : 3, Issue : 1, Year : 2016

Article Page : 74-79

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Abstract

Introduction: Up till now almost all studies used either single intravenous dose of dexamethasone in perioperative period for post operative pain relief or perineurally in regional anesthesia along with local anesthetic agent to prolong the regional anesthesia. The recent animal studies shown the neurotoxicity of perineurally used injection dexamethasone. This study was planned to evaluate the effect of single dose of dexamethasone in infiltration with local anesthetic agent in day care surgical procedure.
Methodology: Cases selection is from ASA – grade I & II patients posted for day care surgical procedure be done under local infiltration anesthesia. The patients are randomly allocated into two groups. Dexamethasone group-GD —25 patients. Control group- GC -26 patients patients were observed for symptoms of perineal itching, effect at the site of local infiltration and PONV. Post operative pain was evaluated half hourly after end of surgical procedure. Pain score is noted by numeric rating scale (NRS) at first pain, after one hour of analgesic and at the time of discharge from the hospital. They were followed up to 7 to 8 days for wound healing and stitch removal.
Observation: The average time of first pain was 259.1 min and 120 min in Group D & C respectively. NRS pain score after rescue analgesic in group D was significantly lower than Group C. Amongst Group D four patients did not required any analgesic till the time of discharge on the same day. From Group C four patients needed additional analgesic Itching at the site of local infiltration perineal itching and PONV was not significant. Conclusion-We conclude that addition of injection dexamethasone with injection lignocaine for local infiltration anesthesia delays the requirement of first analgesic significantly. In addition to this the analgesic effect of injection dexamethasone along with injection diclofinac is highly promising.

Keywords: Analgesia, Day care, Dexamethasone, Infiltration anesthesia, Postoperative pain

How to cite : Subhedar R, Shelke S, Patil R, Subhedar A, Ambre V, Does Dexamethasone Improves Postoperative Day Care Surgery Outcome When Used As Additive To Local Infiltration Anesthesia: A Randomized case control study. Indian J Clin Anaesth 2016;3(1):74-79

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