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To evaluate efficacy and safety of diclofenac transdermal patch with intramuscular diclofenac injection as preemptive analgesia in post operative patients undergoing inguinal hernioplasty

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Original Article

Author Details : Manish Banjare, Kaushal Kishor Kabir*, Arpit Agarwal, K K Arora

Volume : 7, Issue : 1, Year : 2020

Article Page : 99-103

https://doi.org/10.18231/j.ijca.2020.018

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Abstract

Context: To evaluate efficacy and safety of diclofenac transdermal patch with intramuscular diclofenac
injection as preemptive analgesia in post operative patients undergoing inguinal hernioplasty.
Aims: We aim to compare the duration and quality of analgesia provided by diclofenac trans dermal patch
and intramuscular injection and to estimate time at which patients demand rescue analgesia after surgery.
Settings Design: This randomized comparative study was conducted at a tertiary care hospital in central
India.
Materials and Methods: 60 healthy patients divided into two groups of 30 each, scheduled for elective
inguinal hernioplasty under subarachnoid block were taken. Sample size calculation was based on the
difference of means of two independent samples. A transdermal diclofenac patch containing 100 mg of
diclofenac diethylamine was applied to the participants in the study group just before the induction of
anesthesia. In the control group, 75 mg of diclofenac sodium Inj. was given intramuscularly half-an-hour
before the end of surgery.
Data for postoperative pain was assessed at 2, 4, 6, 8, 12, 16 and 24 hours by using a visual analogue scale
(VAS) score and verbal rating scale (VRS) score and analysed using upaired t test.
Results: Statistical difference in duration, quality of pre-emptive analgesia and Significant time of rescue
analgesia was found between the two groups in terms of postoperative pain in patients undergoing inguinal
hernioplasty.
Conclusion: Tran dermal diclofenac patch (100 mg) is a better analgesic route than intramuscular
diclofenac sodium (75 mg) for pre-emptive analgesia in patients undergoing inguinal hernioplasty.

Keywords: Transdermal Patch, Preemptive analgesia, Post operative pain, Visual analogue scale.

How to cite : Banjare M, Kabir K K, Agarwal A, Arora K K, To evaluate efficacy and safety of diclofenac transdermal patch with intramuscular diclofenac injection as preemptive analgesia in post operative patients undergoing inguinal hernioplasty. Indian J Clin Anaesth 2020;7(1):99-103

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