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Comparison of 2-chloroprocaine 1% versus hyperbaric bupivacaine 0.5% for subarachnoid block in pregnant females posted for elective caesarean section

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Original Article

Author Details : Ashwini S, Kumara A B*

Volume : 6, Issue : 4, Year : 2019

Article Page : 532-537

https://doi.org/10.18231/j.ijca.2019.104

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Abstract

Introduction and Objectives: Caesarean sections generally done under subarachnoid block using 0.5%
hyperbaric bupivacaine as the local anaesthetic of choice. As most caesarean sections are of short duration,
we decided to study whether 1% 2-chloroprocaine would be suitable alternative to bupivacaine with primary
outcome being duration of sensory blockade in elective lower segment caesarean sections.
Materials and Methods: In this prospective study, 60 pregnant females belonging to ASA status 1 and
2, posted for elective lower segment caesarean section were equally randomized into two groups. The first
group received 1% chloroprocaine 25 mg (2.5 ml, Group CP) and second group received 0.5% hyperbaric
bupivacaine 10 mg (2.0 ml, Group B), intrathecally. We measured the level of sensory and motor blockade,
duration of sensory blockade and side effects.
Results: Mean duration of sensory blockade was 61.83 23.54 minutes for group CP, which is
significantly shorter than group B which had 174.67 41.17 minutes (p Value <0> clinically significant incidences of hypotension (53.33% Vs 30%) compared to group CP.
Conclusion: Intrathecal low dose 1 % chloroprocaine is a safe and suitable alternative to low dose 0.5%
hyperbaric bupivacaine for an uncomplicated elective lower segment caesarean section.

Keywords: 1% 2-Chloroprocaine 0.5% Hyperbaric bupivacaine, Subarachnoid block, Lower segment caesarean section.

How to cite : Ashwini S, Kumara A B, Comparison of 2-chloroprocaine 1% versus hyperbaric bupivacaine 0.5% for subarachnoid block in pregnant females posted for elective caesarean section. Indian J Clin Anaesth 2019;6(4):532-537

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