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Study on evaluating the effect of Intravenous dexmedetomidine on depth of anaesthesia in patients undergoing lower segment cesarean section under general Anaesthesia

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Original Article

Author Details : G K Jeevapriya, R Selvakumar*

Volume : 6, Issue : 4, Year : 2019

Article Page : 519-522

https://doi.org/10.18231/j.ijca.2019.101

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Abstract

Inroduction & Aims: Awareness and recall causing posttraumatic stress disorder are the major hazards
of General Anaesthesia in cesarean section because of exclusion of Benzodiazepines and opioids in the
anaesthetic management before baby delivery. In this study, dexmedetomidine is used as a sedative &
anxiolytic to abort awareness which was measured using BIS monitor.
Materials and Methods: This study was carried on 50 parturient who were scheduled for elective cesarean
section. They were divided into 2 groups. Group A patients received dexmedetomidine1mcg /kg IVas an
infusion 10 min before induction. Group B patient received normal saline. Trend of BIS scores were
observed at baseline, induction, intubation, skin incision, delivery, closure & extubation. Apgar score at 1
& 5 minutes were recorded. Isolated arm response by placing spygmomanometer cuff on Right forearm
which was inflated before induction was also used to substantiate the presence of conscious awareness.
Results: A median BIS score of 55ranging from42-68 with statistically significant value of P<0> was recorded on all occasions during surgery in the dexmedetomidine group. No statistical significance
was observed in Apgar scores between 2 groups. Negative isolated arm response was noted in the
dexmedetomidine group.
Conclusion : The currently used GA technique was found to be inadequate to abort awareness before baby
delivery. Thereforeby comparing the clinical outcomes like good apgar score and hemodynamic stability,
the use of dexmedetomidine to abolish the awareness during caesarean section was considered as safe.

Keywords: Cesarean section, Dexmeditomidine, BIS score, General Anaesthesia, Apgar score.

How to cite : Jeevapriya G K, Selvakumar R, Study on evaluating the effect of Intravenous dexmedetomidine on depth of anaesthesia in patients undergoing lower segment cesarean section under general Anaesthesia. Indian J Clin Anaesth 2019;6(4):519-522

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